Status:

COMPLETED

An Electronic Clinical Decision Support Tool to Reduce Low-value Antipsychotic Prescriptions

Lead Sponsor:

University of California, Los Angeles

Collaborating Sponsors:

National Institute on Aging (NIA)

Conditions:

Alzheimer Disease

Dementia Alzheimers

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The goal of this study will be to design, implement and test the impact of a quality improvement (QI) intervention that uses an EHR CDS tool among physicians newly ordering an antipsychotic medication...

Detailed Description

Importance: Among patients with Alzheimer's disease and its related dementias (ADRD) with behavioral disturbances, antipsychotic prescriptions have limited efficacy and substantially increase risk of ...

Eligibility Criteria

Inclusion

  • Physicians who will be eligible to receive the EHR CDS tool intervention include those who provide ambulatory care in the UCLA health system and have newly prescribed antipsychotics (e.g., Quetiepine, Olanzapine, Risperidone, Aripiprazole, Haloperidol, Clozapine) for eligible patients (described below) at the medical center in the last 24 months.
  • Eligible patients will be enrolled in the study during their first encounter with one of the randomized physicians (see above) during which a new antipsychotic medication order will be initiated. Inclusion criteria for patients will include: 1) having an assigned primary care physician (PCP) and/or assignment to an Accountable Care Organization (ACO) at UCLA Health, and: 2) being part of the health system's EHR-based dementia registry.

Exclusion

  • Patients who have diagnosis codes for schizophrenic disorders, delusion disorders, bipolar disorders, or other non-organic psychoses on their problem list.
  • Patients with Parkinson's disease on their problem list
  • Patients who have been prescribed antipsychotics in the prior 12 months

Key Trial Info

Start Date :

August 3 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 14 2023

Estimated Enrollment :

158 Patients enrolled

Trial Details

Trial ID

NCT04851691

Start Date

August 3 2021

End Date

August 14 2023

Last Update

September 19 2024

Active Locations (1)

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1

UCLA Health

Los Angeles, California, United States, 90095