Status:
COMPLETED
Strength, Aging, and Memory in Prostate Cancer
Lead Sponsor:
University of Nebraska
Collaborating Sponsors:
American College of Sports Medicine
Conditions:
Prostate Neoplasm
Prostate Cancer
Eligibility:
MALE
19+ years
Brief Summary
The objective of this study is to compare changes in neurocognitive function across a 12-month period between three groups: (1) men treated with androgen deprivation therapy (ADT) for prostate cancer ...
Detailed Description
Aim 1: This study will examine differences in neurocognitive function (cognitive performance, brain structural integrity) from baseline (within 30 days of ADT initiation or 90 days of diagnosis) to 6-...
Eligibility Criteria
Inclusion
- Telephone Interview of Cognitive Status (TICS-M) performance above impaired range (≥21)
- Group-specific criteria:
- First time, primary diagnosis of prostate cancer (ADT+ and ADT-)
- Diagnosed within past 30 days (ADT-)
- Scheduled to receive ≥ 6-months androgen deprivation therapy and have not received \>30 days of androgen deprivation therapy (ADT+)
- Men without a history of cancer who are within one year of age of ADT+ participants (PCa-)
Exclusion
- Second cancer diagnosis (excluding non-invasive skin cancers)
- History of stroke, transient ischemic attack, neurological disorder, or brain surgery involving tissue removal
- Unable to walk without assistance
- Unwilling to complete study requirements
- Body weight greater than 300 pounds (DXA requirement)
- Moderate-intensity physical activity ≥ 150 minutes per week
- Upper and lower body strength training ≥ 2 days per week
- Unable to read in English
Key Trial Info
Start Date :
October 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 26 2023
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04852224
Start Date
October 1 2021
End Date
April 26 2023
Last Update
September 19 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Nebraska Medical Center
Omaha, Nebraska, United States, 68198