Status:

TERMINATED

Immune Response to SARS-CoV-2 (COVID-19) Vaccines in Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Lead Sponsor:

University of Washington

Collaborating Sponsors:

CLL Global Research Foundation

Conditions:

Chronic Lymphocytic Leukemia

Small Lymphocytic Lymphoma

Eligibility:

All Genders

18+ years

Brief Summary

This study evaluates the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL...

Detailed Description

OUTLINE: For patients who have not been vaccinated at the time of enrollment, they will undergo collection of blood samples prior to the first vaccine dose, just before the second vaccine dose, and t...

Eligibility Criteria

Inclusion

  • Age \>= 18 years
  • A diagnosis of chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL)
  • Willing and able to participate in all required evaluations and procedures in this study

Exclusion

  • Any evidence of prior SARS-CoV-2/COVID19 infection

Key Trial Info

Start Date :

March 18 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 1 2024

Estimated Enrollment :

350 Patients enrolled

Trial Details

Trial ID

NCT04852822

Start Date

March 18 2021

End Date

July 1 2024

Last Update

August 2 2024

Active Locations (11)

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Page 1 of 3 (11 locations)

1

City of Hope

Duarte, California, United States, 91010

2

UC Irvine Health/Chao Family Comprehensive Cancer Center

Orange, California, United States, 92868

3

MedStar Georgetown University Hospital

Washington D.C., District of Columbia, United States, 20007

4

University of Miami Miller School of Medicine-Sylvester Cancer Center

Miami, Florida, United States, 33136