Status:

ACTIVE_NOT_RECRUITING

Minimal Residual Disease: A Trial Using Liquid Biopsies in Solid Malignancies.

Lead Sponsor:

University of Leicester

Conditions:

Cancer

Eligibility:

All Genders

18+ years

Brief Summary

The NHS' Genomic Medicine Service offers whole genome sequencing as part of the drive to improve cancer outcomes. It is recognised that actionable mutations (current and emerging), will ultimately imp...

Eligibility Criteria

Inclusion

  • Participant is willing and able to give informed consent for participation in the study.
  • Male or Female, aged 18 years or above.
  • Diagnosed with solid tumour that requires surgical resection, and has a high propensity of relapse.
  • Fit for planned surgical procedure.
  • Able (in the Investigators opinion) and willing to comply with all study requirements.
  • Willing to allow his or her General Practitioner, Consultant, and Clinical Geneticist, if appropriate, to be notified of participation in the study.

Exclusion

  • Female participants who are pregnant, lactating or planning pregnancy during the course of the study.
  • Not fit for surgery.
  • Not willing to donate blood and tissue samples.
  • Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study.
  • Participants who have participated in another research study involving an investigational product in the past 12 weeks.

Key Trial Info

Start Date :

February 16 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

April 30 2026

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT04853420

Start Date

February 16 2021

End Date

April 30 2026

Last Update

May 10 2023

Active Locations (1)

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1

University Hospitals of Leicester

Leicester, United Kingdom