Status:
COMPLETED
Deprescription of Gabapentinoids in Medical Inpatients
Lead Sponsor:
McGill University Health Centre/Research Institute of the McGill University Health Centre
Conditions:
Polypharmacy
Gabapentin
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
In this trial, investigators will distribute educational brochures with information about the deprescription of gabapentinoids (gabapentin and pregabalin) to inpatients in five medical wards spread ac...
Detailed Description
Gabapentinoids, which include gabapentin and pregabalin, are antiepileptic drugs that have been approved by the FDA and Health Canada for the treatment of postherpetic neuralgia, with pregabalin also ...
Eligibility Criteria
Inclusion
- All inpatients 60 years or older admitted to study units who have a gabapentinoid prescription prior to admission
Exclusion
- Less than 60 years of age
- Known seizure disorder
- Not enrolled in the provincial drug plan (RAMQ)
- Opting out of the provincial drug database (Dossier Santé Québec), which will be confirmed with the patient at the time of recruitment
- Previous enrollment in the study
- Patients expected to die before primary endpoint can be realized (e.g., patients admitted for end-of-life care or prognosis of 3 months or less)
- Unable to consent
- Major neurocognitive disorder, as determined by a previously established diagnosis or interim diagnosis by the medical staff on the ward of moderate severity or worse
- Unable to speak English or French
- Insufficient literacy in English or French
- No means of contacting patient by phone after discharge (e.g. no valid phone number, traveling, planned discharge to a facility without means of reaching by phone, etc.)
Key Trial Info
Start Date :
May 28 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 7 2023
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT04855578
Start Date
May 28 2021
End Date
December 7 2023
Last Update
January 30 2024
Active Locations (2)
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1
Montreal General Hospital
Montreal, Quebec, Canada, H3G 1A4
2
Royal Victoria Hospital
Montreal, Quebec, Canada, H4A 3J1