Status:

COMPLETED

Antimicrobial Photodynamic Therapy in Chronic Periodontitis and Diabetes Mellitus

Lead Sponsor:

King Saud University

Conditions:

Type 2 Diabetes Mellitus

Prediabetic State

Eligibility:

All Genders

30-60 years

Phase:

PHASE2

PHASE3

Brief Summary

With this design, this study hypothesizes that; (i) ICG-PDT would produce superior clinical, microbiological, and immune-inflammatory outcomes as compared to RSD and (ii) ICG-PDT would produce equal e...

Eligibility Criteria

Inclusion

  • aged ≥30 years
  • clinically diagnosed with mild to moderate periodontitis
  • self-reported type-2 DM for ≥2 years confirmed by a physician with HbA1c levels ≥6.5%
  • patients who complied with the treatment protocol.

Exclusion

  • (i) pregnancy and lactation (ii) who had taken antibiotics in the previous 3 months (iii) who had undergone periodontal therapy or any decontamination treatment in their oral cavity in the previous 6 months (iv) former/current smokers (v) failure to provide a signed informed consent.

Key Trial Info

Start Date :

June 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2021

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT04857346

Start Date

June 1 2020

End Date

February 1 2021

Last Update

April 23 2021

Active Locations (1)

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College of Applied Medical Sciences, King Saud University

Riyadh, Saudi Arabia, 11454