Status:

COMPLETED

Memantine Augmentation of Targeted Cognitive Training in Schizophrenia

Lead Sponsor:

University of California, San Diego

Conditions:

Schizophrenia

Schizoaffective Disorder

Eligibility:

All Genders

18-65 years

Phase:

PHASE2

PHASE3

Brief Summary

Treatment of schizophrenia currently includes antipsychotic medications and cognitive therapies which improve some symptoms, but do not sufficiently restore cognitive functioning or reduce psychosocia...

Detailed Description

Treatment of schizophrenia (SZ) currently includes antipsychotic medications and cognitive therapies which improve some symptoms, but do not sufficiently restore cognitive functioning or reduce psycho...

Eligibility Criteria

Inclusion

  • DSM-IV diagnosis of schizophrenia or schizoaffective disorder
  • Written informed consent to participate in the study
  • Age 18-65
  • Absence of dementia or mental retardation
  • Urine toxicology negative for recreational drugs
  • Fluent and literate in English

Exclusion

  • Meets DSM-IV criteria for current substance abuse or dependence and has been substance abstinent for less than 30 days
  • A history of traumatic brain injury
  • Auditory or visual impairments severe enough to prevent study participation
  • Under conservatorship (determined by Anasazi)
  • Pregnancy

Key Trial Info

Start Date :

July 6 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 30 2025

Estimated Enrollment :

62 Patients enrolled

Trial Details

Trial ID

NCT04857983

Start Date

July 6 2021

End Date

March 30 2025

Last Update

April 30 2025

Active Locations (1)

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1

Clinical Teaching Facility (CTF B-403 at UCSD Medical Center)

San Diego, California, United States, 92103