Status:
COMPLETED
Inhibition of Non-histaminergic Pruritus Applied Using 3 Different Pruritogens
Lead Sponsor:
Aalborg University
Conditions:
Itch
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
With this experiment, we want to use to investigate whether repeated application of EMLA cream as a tool to modulate non-histaminergic itching, which is produced using small needles from the plant muc...
Eligibility Criteria
Inclusion
- Healthy men and women
- 18-60 years
- Speak and understand English
Exclusion
- Pregnancy or lactation
- Drug addiction defined as any use of cannabis, opioids or other drugs
- Previous or current neurologic, musculoskeletal or mental illnesses that may affect the results (e.g. neuropathy, muscular pain in the upper extremities, etc.).
- Lack of ability to cooperate
- Current use of medications that may affect the trial such as antihistamine medications or pain killers.
- Skin diseases
- Hypersensitivity to papaya and mango fruit, cashew nuts and rubber latex
- Consumption of alcohol or painkillers 24 hours before the study days and between these
- Acute or chronic pain
- Participation in other trials within 1 week of study entry (4 weeks in the case of pharmaceutical trials)
- Known history of anaphylactic shock, or local allergy (contact dermatitis) to lidocaine, prilocaine or other local anaesthetics of the amide type.
Key Trial Info
Start Date :
November 15 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2022
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT04858360
Start Date
November 15 2021
End Date
October 1 2022
Last Update
January 18 2023
Active Locations (1)
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1
Aalborg University
Aalborg, Denmark, 9220