Status:

ACTIVE_NOT_RECRUITING

Evaluation of Regeneten Augmentation for Subscapularis Healing After Total Shoulder Arthroplasty (RESTOR)

Lead Sponsor:

Ohio State University

Collaborating Sponsors:

Smith & Nephew, Inc.

Conditions:

Arthroplasty, Replacement, Shoulder

Eligibility:

All Genders

50+ years

Phase:

NA

Brief Summary

The purpose of this study is to evaluate whether augmentation of subscapularis repair with the Regeneten implant after anatomic total shoulder arthroplasty (TSA) can improve rates of subscapularis hea...

Detailed Description

Subscapularis management is an area of controversy in the literature for total shoulder arthroplasty (TSA). Regeneten has been suggested as a bioinductive implant to aid in rotator cuff healing. We hy...

Eligibility Criteria

Inclusion

  • Patients healthy enough to undergo primary anatomic TSA
  • Being treated with subscapularis tenotomy or subscapularis peel.
  • Age 50 or above
  • Intact rotator cuff including subscapularis as determined by preoperative examination and imaging (typically preoperative CT, MRI if indicated or available).

Exclusion

  • Revision arthroplasty
  • Reverse arthroplasty
  • Requiring a lesser tuberosity osteotomy
  • Intraoperative identification of rotator cuff tear requiring repair
  • Object to using cow derived material
  • Prior index shoulder surgery requiring treatment to the subscapularis

Key Trial Info

Start Date :

July 14 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2027

Estimated Enrollment :

75 Patients enrolled

Trial Details

Trial ID

NCT04861714

Start Date

July 14 2020

End Date

April 1 2027

Last Update

July 31 2025

Active Locations (1)

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The Ohio State University Sports Medicine Center

Columbus, Ohio, United States, 43221