Status:

TERMINATED

Registrational Trial to Compare Effectiveness of Two Digital Software Medical Devices as Adjunctive Oncology Treatment

Lead Sponsor:

Blue Note Therapeutics

Conditions:

Anatomic Stage I Breast Cancer AJCC v8

Anatomic Stage II Breast Cancer AJCC v8

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

This is a non-significant risk, double-blinded, randomized, registrational study to compare the effectiveness of two digital, software only, medical devices (SaMD) (attune™ and cerena™) in reducing ca...

Eligibility Criteria

Inclusion

  • Stage I-III breast cancer or Stage I-III NSCLC who are currently in active treatment or have completed initial cancer directed treatments (surgery, radiation, chemotherapy) within the past 3 months;
  • Are experiencing at least moderate anxiety (GAD-7 \>10) or mild-to-moderate depression (PHQ-8 score 5-11);
  • Are fluent in English; and
  • Have access to smartphone, or tablet capable of running iOS or Android software.

Exclusion

  • Previous history of cancer;
  • \<2-yr survival prognosis as determined by treating clinician;
  • Currently participating in investigative CBT trial for treatment of anxiety or depression;
  • Participant is unable to complete training, has cognitive deficits, more severe psychiatric conditions, lack of access to internet accessible device or psycho-social conditions (e.g., other social conditions, that would interfere with adherence to self-directed care), such that in investigator's opinion the participant would be unable to complete the study;
  • Recently completed use of Blue Note Therapeutics Covid Cancer Care Program or other Blue Note Therapeutics-sponsored study; and
  • PHQ-9 Q9 response \>0 AND Columbia Suicide Severity Risk Scale (or equivalent) score of Category 2- "suicidal ideation" at screening.

Key Trial Info

Start Date :

May 15 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2022

Estimated Enrollment :

31 Patients enrolled

Trial Details

Trial ID

NCT04862195

Start Date

May 15 2021

End Date

September 1 2022

Last Update

September 13 2022

Active Locations (13)

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Page 1 of 4 (13 locations)

1

OPN Healthcare

Glendale, California, United States, 91203

2

Oncology Physicians Network Healthcare

Los Alamitos, California, United States, 90720

3

Redlands Oncology

Redlands, California, United States, 92373

4

Eastern CT Hematology and Oncology Associates

Norwich, Connecticut, United States, 06360