Status:

COMPLETED

Effect of Beta-alanine and Pelvic Floor Muscle Training on Urinary Incontinence After Radical Prostatectomy (BELA)

Lead Sponsor:

University Hospital Olomouc

Collaborating Sponsors:

Palacky University

Conditions:

Prostate Cancer

Urinary Incontinence

Eligibility:

MALE

40-80 years

Phase:

NA

Brief Summary

The purpose of this study is to evaluate the effectiveness of beta-alanine in combination with pelvic floor muscle training (PFMT) compared to PFMT plus placebo in men undergoing radical prostatectomy...

Detailed Description

This study will assess efficacy of beta-alanine in combination with PFMT for the treatment of participants with urinary incontinence after radical prostatectomy. B-alanine is a component of L-carnosin...

Eligibility Criteria

Inclusion

  • Age 40-80 years
  • Able to give informed consent
  • Histologically proven prostate cancer
  • BMI \<35
  • No other cancer treatment
  • Continent
  • Good physical and mental activity
  • On normal diet
  • Scheduled for radical prostatectomy (open or robotic)

Exclusion

  • Other malignant cancer (except for benign skin cancer)
  • Age \> 80 years
  • Diabetes mellitus (any type)
  • Chronic bowel inflammatory disease
  • Urinary incontinence
  • Impaired mental activity
  • Previous radiotherapy of hormonal therapy
  • Vegetarian/vegan/on macrobiotic diet

Key Trial Info

Start Date :

February 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2022

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT04862533

Start Date

February 1 2020

End Date

October 1 2022

Last Update

December 16 2022

Active Locations (1)

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University hospital Olomouc

Olomouc, Czechia, 77900