Status:

ACTIVE_NOT_RECRUITING

Accelerating Lung Cancer Diagnosis Through Liquid Biopsy

Lead Sponsor:

University Health Network, Toronto

Collaborating Sponsors:

Lung Health Foundation

The Princess Margaret Cancer Foundation

Conditions:

Non-small Cell Lung Cancer

Eligibility:

All Genders

18+ years

Brief Summary

This study will assess the utility of liquid biopsy to accelerate the time to treatment for patients with newly diagnosed advanced non-small cell lung cancer, compared to the conventional diagnostic p...

Eligibility Criteria

Inclusion

  • Lung RAMP Multidisciplinary Cancer Conference or study team confirms radiologic (clinical) evidence of advanced, unresectable lung cancer;
  • Measurable disease (presumed malignant) by RECIST 1.1;
  • Age ≥18 years;
  • Ability to provide written informed consent;
  • Diagnostic biopsy and molecular profiling ordered or planned. Patients remain eligible even if biopsy or tumour testing later fails or is deemed not feasible.

Exclusion

  • Pregnancy;
  • Concurrent active malignancy except for localized non-melanomatous skin cancer or non-invasive cervical cancer. Any previous cancer (excluding NSCLC) must have been treated more than 2 years prior to study entry with no current evidence of active disease.

Key Trial Info

Start Date :

January 14 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2026

Estimated Enrollment :

170 Patients enrolled

Trial Details

Trial ID

NCT04863924

Start Date

January 14 2021

End Date

December 1 2026

Last Update

December 18 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

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Princess Margaret Cancer Centre

Toronto, Canada