Status:
UNKNOWN
DNA Adductomics for Colorectal Cancer Investigation
Lead Sponsor:
University of Copenhagen
Collaborating Sponsors:
Hvidovre University Hospital
Conditions:
Colorectal Cancer
Familial Adenomatous Polyposis
Eligibility:
All Genders
18+ years
Brief Summary
This project seeks to identify DNA-adducts in colon tissue from different groups of patients with CRC scheduled for complete or partial colon resections. Other patients scheduled for resection of the ...
Detailed Description
Colorectal cancer (CRC) develops as a result of multiple genetic mutations causing normal intestinal epithelium to transform into a colorectal carcinoma. Genetic mutations may be caused by many differ...
Eligibility Criteria
Inclusion
- Patients with either FAP, Lynch syndrome, other HNPCC, sporadic colorectal cancer, ulcerative colitis or other conditions who are scheduled for whole or partial resection of their colon
Exclusion
- Any condition that makes the investigator or hospital personnel doubt that voluntary participation isfeasible.
- Patients who are not able to understand and sign the informed consent form for any reason, including lack of a sufficient period of time to consider their participation.
- Patients who are below 18 years of age.
- Patients who donated blood to a blood bank within 3 months prior to their operation.
Key Trial Info
Start Date :
February 15 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04865601
Start Date
February 15 2021
End Date
December 31 2025
Last Update
November 30 2023
Active Locations (1)
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1
Department of Nutrition, Exercise and Sports, University of Copenhagen
Copenhagen, Frederiksberg C, Denmark, 1958