Status:
COMPLETED
Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part III
Lead Sponsor:
University of Roma La Sapienza
Conditions:
Wound Heal
Wound Surgical
Eligibility:
All Genders
30-50 years
Phase:
NA
Brief Summary
The purpose of the present study is to evaluate the effect of Hyaluronic acid application in the gene expression profile and cellular behavior in the early wound healing process -24 hours after injury...
Detailed Description
Although it has been demonstrated the role of HA in many different biological process related with tissue repair and regeneration, specific mechanisms involved in the early wound healing process in th...
Eligibility Criteria
Inclusion
- patients that required periodontal surgery;
- patients age between 30-60 years;
- patients with full mouth plaque score and full mouth bleeding score \< 15%;
- patients with a good general healthy status;
- patients without any medicaments or drug consumption that can affect the healing process;
- non-smoking patients.
Exclusion
- patients in pregnancy;
- patients in lactation period;
- patients with consumption of antibiotics or anti-inflammatory drugs in the previous six months;
- patients with systemic diseases.
Key Trial Info
Start Date :
April 29 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 6 2021
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT04865952
Start Date
April 29 2021
End Date
July 6 2021
Last Update
October 4 2022
Active Locations (1)
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1
Department of Oral and Maxillofacial Sciences. Section of Periodontics.Sapienza, University of Rome
Roma, Italy, 00161