Status:

COMPLETED

Drug Use Study With VYVANSE® in Australia for Binge Eating Disorder

Lead Sponsor:

Shire

Conditions:

Binge-eating Disorder

Eligibility:

All Genders

18-55 years

Brief Summary

This study will check how and to whom Vyvanse is prescribed in Australia by retrospectively analyzing a prescription database with additional information provided by a physician survey.

Detailed Description

This is a drug utilization study (DUS) using cross-sectional database analysis of participants who are prescribed lisdexamfetamine dimesylate for treatment of BED. The study will combine data from two...

Eligibility Criteria

Inclusion

  • Main prescription data analysis:
  • \- At least one prescription for lisdexamfetamine dimesylate recorded in the NostraData database in Australia.
  • For all sensitivity analyses (sensitivity analysis I, II and III):
  • \- At least one prescription for lisdexamfetamine dimesylate recorded in the NostraData database in Australia during the defined observation period of the study.
  • Physician survey:
  • \- The physician prescribed lisdexamfetamine dimesylate for indications other than ADHD in the last 12 months for at least one participant.
  • Participant population:
  • \- Physician entered data for the participant until at least question 3 (treatment information (Q03); main indication).

Exclusion

  • For all sensitivity analyses (sensitivity analysis I, II and III):
  • Evidence of use for lisdexamfetamine dimesylate for treatment of ADHD, as shown by prescription records for ADHD medication other than lisdexamfetamine dimesylate at any time.
  • Record of at least one lisdexamfetamine dimesylate prescription prior to launch of lisdexamfetamine dimesylate for BED (02/17/2018).
  • Additional exclusion criteria for the specific sensitivity analyses:
  • For sensitivity analysis I:
  • \- Prescriptions for lisdexamfetamine dimesylate issued by pediatricians or child psychiatrists.
  • For sensitivity analysis II:
  • \- Prescriptions for lisdexamfetamine dimesylate issued by all prescribers other than psychiatrists (example, pediatricians, general practitioner \[GPs\]).
  • For sensitivity analysis III:
  • Prescriptions for lisdexamfetamine dimesylate issued by pediatricians or child psychiatrists.
  • For participants with age available, participants with evidence for age at first prescription below 18 years.
  • Physician survey and participant population:
  • \- Physician entered ADHD as main indication for prescription of lisdexamfetamine dimesylate (treatment information \[Q03\]) for the participant.

Key Trial Info

Start Date :

June 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 15 2021

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT04866043

Start Date

June 1 2019

End Date

October 15 2021

Last Update

November 22 2021

Active Locations (1)

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Site

Sydney, New South Wales, Australia, 2000