Status:
COMPLETED
RCT of tDCS Combined With Cognitive Training in Schizophrenia
Lead Sponsor:
CHAN SAU MAN, SANDRA
Conditions:
Schizophrenia
Eligibility:
FEMALE
18-65 years
Phase:
NA
Brief Summary
Given the superior effects of CT augmented tDCS in healthy subjects, the aim of the current study was to examine whether the effect of CT on cognition can be enhanced with concurrent anodal tDCS in sc...
Detailed Description
The current study is a parallel-group, double-blinded, randomised controlled trial that aimed to fill the knowledge gap in investigating the effect of five sessions of concurrent cognitive training wi...
Eligibility Criteria
Inclusion
- Participants aged 18-65 years old; and
- Being right handed; and
- Able to communicate in Cantonese; and
- With the diagnosis of schizophrenia meeting the diagnostic criteria of the World Health Organization's 10th version of the International Statistical Classification of Disease and Related Health Problems (ICD-10). All diagnoses were ascertained at multidisciplinary team and endorsed by at least a consultant psychiatrist and a specialist in psychiatry in the clinical teams based in Tai Po Hospital.
Exclusion
- Significant neurologic history such as dementia, stroke, seizure, Parkinson's disease, multiple sclerosis; or
- History of brain neurosurgery; or
- Active abuse of alcohol or illicit substances; or
- Concurrent use of cognitive-enhancing medications e.g. acetylcholinesterase inhibitors; or
- Documented history of learning disability; or
- Implanted with pacemakers, intracranial electrodes, defibrillators, metal implants in head or neck area; or
- Pregnancy or breastfeeding; or
- Changes in medication regime over the two weeks before or during the study period (Brunoni, Ferrucci, et al., 2011).
Key Trial Info
Start Date :
August 23 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2020
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT04870996
Start Date
August 23 2019
End Date
June 30 2020
Last Update
May 4 2021
Active Locations (1)
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1
Department of Psychiatry, CUHK
Hong Kong, Hong Kong, 852