Status:
COMPLETED
The Effects of Enzyme-rich Malt Extract on Chronic Constipation
Lead Sponsor:
The Functional Gut Clinic
Conditions:
Constipation
Quality of Life
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Participants with constipation will take enzyme-rich malt extract for 4 weeks whilst completing a daily bowel habit diary before and during intervention.
Detailed Description
This pilot study is an open label, pre-post interventional study to evaluate the use of ERME in the treatment of people with chronic constipation. This study involves eligible participants that have ...
Eligibility Criteria
Inclusion
- Participant has diagnosis of chronic constipation according to the KESS score.
- Participant can communicate and understand English.
- Participant has a body mass index (BMI) between 18.5 and 34.9kg/m2 (bounds included).
Exclusion
- Dependant use of opioid-based medications.
- New use of prokinetic therapy during the study.
- Use of antibiotics in the last 4 weeks.
- Use of probiotics in the last 2 weeks.
- Organic gastrointestinal disease, including inflammatory bowel disease (IBD), coeliac disease and diverticulitis.
- Participant has known mechanical obstruction of the GI tract.
- Participant has diabetes.
- Participant has any hepatic disease.
- Participant has any disease of the CNS.
- Participant has had previous abdominal or colorectal surgery including appendectomy, cholecystectomy, and hysterectomy.
- Participant has intake of ERME for 2 weeks before the study.
Key Trial Info
Start Date :
March 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2022
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04873466
Start Date
March 1 2021
End Date
March 1 2022
Last Update
September 23 2022
Active Locations (1)
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1
The Functional Gut Clinic
Manchester, Greater Manchester, United Kingdom, M2 4NG