Status:
RECRUITING
LT for Unresectable Colorectal Liver Metastasis
Lead Sponsor:
Seoul National University Hospital
Conditions:
Liver Metastasis Colon Cancer
Eligibility:
All Genders
19+ years
Phase:
NA
Brief Summary
Unlike hepatocellular carcinoma, liver transplantation in patients with liver metastasis from colorectal cancer is limited in only few centers. Previously, it was not generally implemented due to lack...
Detailed Description
Surgical treatment offers a distinct survival benefit in liver metastasis of colorectal cancer (CRC LM). However, it has been estimated that only 40% of patients are candidates for curative liver rese...
Eligibility Criteria
Inclusion
- Proven colorectal cancer liver metastases without no other treatment (such as immunotherapy, chemotherapy, surgical resection, and radiofrequency ablation)
- Metastasis isolated to liver
- Patients selected as a liver transplant recipient at a multidisciplinary meeting
- Paitents with a willing, healthy living donor
- Willing and able to provide written informed consent
Exclusion
- Pregnant women
- Known history of human immunodeficiency virus (HIV) infection
- Patients with active peptic ulcer within 2 weeks of transplantation
- Persistent colorectal cancer after colon resection
- Hemodynamically unstable prior to liver transplantation
- Progression of LM at any timepoint prior to transplant surgery (assessed in a multidisciplinary meeting)
Key Trial Info
Start Date :
August 22 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2026
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04874259
Start Date
August 22 2022
End Date
May 1 2026
Last Update
September 6 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Seoul National University Hospital
Seoul, South Korea, 03080