Status:
COMPLETED
Dexametasone Versus Dexametasone Plus Dexmedetomidine in Nerve Blocks
Lead Sponsor:
University of Chile
Conditions:
Analgesia
Pain, Acute
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
This study will compare perineural dexamethasone 2mg and perineural mixture of dexamethasone 2mg plus dexmedetomidine 50mcg DX plus DXD as adjuvants to local anesthetics for ultrasound-guided infracla...
Detailed Description
With the approval of Ethics Committee of the Hospital Clínico Universidad de Chile, a total of 50 patients undergoing upper extremity surgery (elbow and below) will be recruited. Recruitment will be c...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologists classification 1-3
- Body mass index between 20 and 35
Exclusion
- Adults who are unable to give their own consent
- Pre-existing neuropathy (assessed by history and physical examination)
- Coagulopathy (assessed by history and physical examination and, if deemed clinically necessary, by blood work up i.e. platelets ≤ 100, International Normalized Ratio ≥ 1.4 or prothrombin time ≥ 50)
- Renal failure (assessed by history and physical examination and, if deemed clinically necessary, by blood work up i.e. creatinine ≥ 100)
- Hepatic failure (assessed by history and physical examination and, if deemed clinically necessary, by blood work up i.e. transaminases ≥ 100)
- Allergy to local anesthetics (LAs)
- Pregnancy
- Prior surgery in the infraclavicular region
- Chronic pain syndromes requiring opioid intake at home
Key Trial Info
Start Date :
August 31 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2022
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04875039
Start Date
August 31 2021
End Date
March 1 2022
Last Update
March 4 2022
Active Locations (1)
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1
Hospital Clínico Universidad de Chile
Santiago, Metropolitan, Chile