Status:
ENROLLING_BY_INVITATION
UVA-1 for Treatment of Skin Tightening and Improvement of Hand Function in Scleroderma
Lead Sponsor:
University of Utah
Conditions:
Scleroderma
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
UVA-1 has been reported to be beneficial to skin changes in scleroderma in several case reports and a few small studies. (Jacobe 2020) Interpretation of these reports has been difficult based on the s...
Detailed Description
Systemic sclerosis (SSc), also called scleroderma, is a rare chronic autoimmune disease that can have a wide range of cutaneous, joint, and internal organ involvement. In the skin, SSc is characterize...
Eligibility Criteria
Inclusion
- Must be able to understand and provide written informed consent
- Scleroderma skin involvement affecting both hands approximately equally
- Age of at least 18-years-old
- Male or female
- Ability to engage in twice weekly UVA1 sessions
- No changes in systemic therapy during the first 100 days of the study period
Exclusion
- On photosensitizing medication
- Inability to complete study visits
- UV light therapy in the 4 weeks prior to entering the study
- Commercial tanning or excessive sun exposure in the 4 weeks prior to entering the study
- Current pregnancy or planned pregnancy during the study period
- Use of topical therapies other than emollients (suprapotent corticosteroids) in the 2 weeks prior to entering the study
- History of intolerance to ultraviolet light
- Any other condition that will disqualify the patient from the study in the opinion of the investigator
Key Trial Info
Start Date :
December 12 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04875078
Start Date
December 12 2020
End Date
December 1 2025
Last Update
December 18 2024
Active Locations (1)
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1
University of Utah MidValley Dermatology
Murray, Utah, United States, 84107