Status:
RECRUITING
Phenotype, Genotype and Biomarkers 2
Lead Sponsor:
University of Miami
Collaborating Sponsors:
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Amyotrophic Lateral Sclerosis
Hereditary Spastic Paraplegia
Eligibility:
All Genders
7+ years
Brief Summary
The purpose of this study is to learn more about amyotrophic lateral sclerosis (ALS) and other related neurodegenerative diseases, including frontotemporal dementia (FTD), primary lateral sclerosis (P...
Eligibility Criteria
Inclusion
- Inclusion Criteria for affected individuals (primary participants) include:
- Clinical diagnosis or suspicion of ALS or a related disorder, including, but not limited to, ALS-FTD, PLS, HSP, FTD, Multisystem Proteinopathy (MSP) and PMA.
- Subject is able and willing to comply with study procedures
- Exclusion Criteria for affected individuals (primary participants) include:
- Subjects with a condition or who are in a situation which, in the PI's opinion, could confound the study finding or may interfere significantly with the individual's participation and compliance with the study protocol -- including but not limited to neurological, psychological and/or medical conditions
- Inclusion criteria for biological family members (secondary participants) include:
- Family member of an enrolled affected primary participant
- Exclusion Criteria for biological family members (secondary participants) include:
- Subjects with a condition or who are in a situation which, in the PI's opinion, could confound the study finding or may interfere significantly with the individual's participation and compliance with the study protocol -- including but not limited to neurological, psychological and/or medical conditions
Exclusion
Key Trial Info
Start Date :
January 8 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 1 2028
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT04875416
Start Date
January 8 2021
End Date
August 1 2028
Last Update
August 28 2025
Active Locations (4)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Miami
Miami, Florida, United States, 33136
2
University of Kansas Medical Center
Kansas City, Kansas, United States, 66160
3
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
4
University of Cape Town
Cape Town, South Africa