Status:

RECRUITING

Sonification Techniques for Gait Training

Lead Sponsor:

Istituti Clinici Scientifici Maugeri SpA

Conditions:

Parkinson Disease

Stroke

Eligibility:

All Genders

Up to 80 years

Phase:

NA

Brief Summary

Music therapy is widely used in relational and rehabilitation settings. In addition to Neurologic Music Therapy and other music-based techniques, "sonification" approaches were recently introduced in ...

Detailed Description

Background: Music therapy is widely used in relational settings. The sound can engage limbic and paralimbic areas and a variety of other brain areas strictly connected with movement (motor cortex, su...

Eligibility Criteria

Inclusion

  • Inclusion criteria (stroke patients)
  • Age \< 80
  • Mini Mental State Examination \> 24
  • Modified Rankin Scale: 1-3
  • Single hemisphere lesion
  • Stabilized disease (\> 6 months after the acute event)
  • Impairment in gait parameters (e.g. velocity, perceived fatigue etc)
  • Motor independence during walking (without orthotic devices and aids) but with pathological pattern (spasticity level: Ashworth \< 2)
  • Inclusion criteria (patients with Parkinson's disease)
  • Age \< 80
  • Mini Mental State Examination \> 24
  • Unified Parkinson Disease Rating Scale score (Parte III): \< 28
  • Stabilized disease and drug therapy
  • Altered gait patterns
  • Motor independence during walking (without orthotic devices and aids) but with pathological pattern
  • Inclusion criteria (patients with multiple sclerosis):
  • Age \< 60
  • Mini Mental State Examination \> 24
  • Expanded Disability Status Scale score: 3-5
  • Stabilized disease in the last 6 months (without relapse or disability progression)
  • Altered gait patterns (i.e., careening, slowing down, spasticity: Ashworth \< 2, etc.)
  • Motor independence during walking
  • Exclusion Criteria (stroke patients)
  • Multiple or bilateral lesions
  • Neglect
  • Equinism
  • Spasticity: Ashworth \>2
  • Structured (non-elastic) Achilles tendon retraction
  • Neurotoxin in the 3 months prior to the study
  • Baclofen introduced or modified in the week before the start of the study
  • Previous or concurrent diseases disabling the lower limb functions
  • Rehabilitative treatments with music in the year before the study
  • Exclusion criteria (patients with Parkinson's disease):
  • Previous or concurrent diseases disabling the lower limb functions
  • Changes of drug therapy during the study
  • Rehabilitative treatments with music in the year before the study
  • Exclusion criteria (patients with multiple sclerosis):
  • Previous or concurrent diseases disabling the lower limb functions
  • Neurotoxin in the 3 months prior to the study
  • Baclofen introduced or modified in the week before the start of the study
  • Spasticity: Ashworth \>2
  • Structured (non-elastic) Achilles tendon retraction
  • Rehabilitative treatments with music in the year before the study

Exclusion

    Key Trial Info

    Start Date :

    January 18 2021

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    June 30 2026

    Estimated Enrollment :

    120 Patients enrolled

    Trial Details

    Trial ID

    NCT04876339

    Start Date

    January 18 2021

    End Date

    June 30 2026

    Last Update

    May 11 2025

    Active Locations (1)

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    1

    Istituti Clinici Scientifici Maugeri IRCCS

    Pavia, Italy, 27100