Status:
UNKNOWN
Monocytes as Predictors of Cystic Fibrosis-related Bone Disease
Lead Sponsor:
Université de Reims Champagne-Ardenne
Conditions:
Cystic Fibrosis
Eligibility:
All Genders
20-65 years
Brief Summary
Hypothesis: Circulating monocytes RANK and MCSF-R expression is predictive of Cystic Fibrosis-related Bone Disease. Study design: Single-center comparative cross-sectional study Population: Patients ...
Eligibility Criteria
Inclusion
- Patients between 20 and 65 years (+/- 2 years)
- Patients of the CRCM of Reims University Hospital
- Patients with at least one CF causing mutation in CFTR gene
- Patients agreeing to participate in the study (informed consent form)
- Patients fluent in French
- Patients affiliated with a social security regimen
- Healthy donors between 20 and 65 years (+/- 2 years)
- Healthy donors giving blood at EFS GE, Reims
- Healthy donors agreeing to participate in the study (informed consent form)
- Healthy donors fluent in French
- Healthy donors affiliated with a social security regimen
- Healthy donors whose characteristics agree with the ALC/PIL/DIR/AJR /FO/606 convention between EFS GE, Reims, and Reims Champagne-Ardenne University
Exclusion
- Patient having a medical history that may compromise the protocol (psychiatric, medical or pharmacological disorders such as the use of anti-inflammatory drugs, or any compound that may alter or modify the inflammatory reaction in the week preceding the protocol).
- Pregnant or breastfeeding women
- Patient with eating disorders (anorexia, bulimia, overeating)
- Patient protected by law (guardianship, curatorship, hospitalized without their consent and not protected by law, deprived of liberty)
Key Trial Info
Start Date :
June 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 1 2025
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04877223
Start Date
June 1 2021
End Date
November 1 2025
Last Update
May 18 2022
Active Locations (1)
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1
Université de Reims Champagne-Ardenne
Reims, France