Status:
UNKNOWN
Troponin T and Emergency High-risk Abdominal Surgery
Lead Sponsor:
Copenhagen University Hospital, Hvidovre
Conditions:
Emergency Laparotomy
Inflammatory Response
Eligibility:
All Genders
18+ years
Brief Summary
To assess whether perioperatively elevated TnT levels, using high sensitivity troponin T (hsTnT) measurements, are associated with an increased risk of postoperative mortality as well as severe postop...
Detailed Description
Cardiac Troponin T (TnT) is a cardiac-specific molecule, released into the systemic circulation following myocardial cell injury. The release of cardiac Troponins is common during critical illness and...
Eligibility Criteria
Inclusion
- Adults (18 years or over) undergoing emergency laparotomy or laparoscopy for following abdominal pathology:
- Intestinal obstruction
- Perforated viscus
- Intestinal ischemia
- Intraabdominal bleeding
- The above conditions include both primary surgery and re-operation after elective surgery.
Exclusion
- Patients undergoing
- Appendicectomies
- Negative laparoscopies/laparotomies
- Cholecystectomies
- Simple herniotomies following incarceration without bowel resection
- Reoperation due to fascial separation with no other abdominal pathology identified
- Internal hernia after Roux-en-Y gastric bypass surgery
- Subacute surgery (surgery planned within 48 h) for inflammatory bowel diseases
- Subacute colorectal cancer surgery
- Patients with missing hsTnT values on both postoperative day 1 and 2
Key Trial Info
Start Date :
March 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 31 2022
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT04878159
Start Date
March 1 2021
End Date
July 31 2022
Last Update
May 11 2021
Active Locations (1)
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1
Copenhagen University Hospital Hvidovre
Hvidovre, Denmark