Status:
COMPLETED
Calcitonin Gene-related Peptide Expression in Human Periodontal Ligament
Lead Sponsor:
Institucion Universitaria Colegios de Colombia
Collaborating Sponsors:
Universidad Santo Tomas
Conditions:
CGRP Expression in Human Periodontal Ligament
Eligibility:
All Genders
18-27 years
Phase:
NA
Brief Summary
The purpose of this study was to quantify the effect of moderate and severe orthodontic forces on Calcitonin gene-related peptide expression in the healthy human periodontal ligament. Methodology: 90...
Detailed Description
An experimental study was performed according to Colombian Ministry of Health recommendations regarding ethical issues in research involving human tissue. Written informed consent was obtained from ea...
Eligibility Criteria
Inclusion
- \- Premolars extraction indicated for orthodontic reasons with complete root development determined radiographically (and confirmed visually after extraction)
Exclusion
- Medicated patients,
- Smokers patients,
- Premolars with caries or restorations,
- Premolars with signs of periodontal disease or traumatic occlusion,
- Premolars with previous orthodontic forces
Key Trial Info
Start Date :
June 4 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 10 2020
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT04881786
Start Date
June 4 2019
End Date
March 10 2020
Last Update
May 13 2021
Active Locations (1)
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1
Universidad Santo Tomas
Bucaramanga, Metropolitana, Colombia