Status:
UNKNOWN
Study of the Incidence of Jarisch-Herxheimer Reaction in Leptospirosis Patients in New Caledonia
Lead Sponsor:
Institut Pasteur
Conditions:
Leptospirosis
Jarisch Herxheimer Reaction
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The objective of the study is to estimate the incidence of Jarisch-Herxheimer Reactions (JHR) during antibiotic treatment of human leptospirosis cases in New Caledonia. Participants are patients mana...
Detailed Description
The objective of the study is to estimate the incidence of Jarisch-Herxheimer Reactions (JHR) during antibiotic treatment of human leptospirosis cases in New Caledonia. Secondary objectives of the st...
Eligibility Criteria
Inclusion
- Be over 18 years of age (at the time of inclusion);
- Be suspected of developing leptospirosis by the clinician in one of the 5 participating centres
- Have been informed of the use of their samples for non-therapeutic scientific research purposes by a note and information sheet established by the Institut Pasteur of New Caledonia (IPNC) and the Institut Pasteur Paris (IPP), provided and explained by the inclusion centre.
- Have expressed their oral consent to participate in this research project
- Non inclusion criteria:
- Under 18 years of age
- Have not given oral consent to participate
- Have a chronic inflammatory disease.
- Having concomitant antibiotic and/or anti-inflammatory treatment or medical management incompatible with the purpose of the study,
- Pregnant or breastfeeding women.
Exclusion
- \- Leptospirosis diagnostic is not confirmed by molecular biology. Complete destruction of the corresponding samples will be ensured. Clinical data and biological analyses will also be removed from the data associated with the research.
Key Trial Info
Start Date :
July 23 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2023
Estimated Enrollment :
900 Patients enrolled
Trial Details
Trial ID
NCT04882046
Start Date
July 23 2021
End Date
December 1 2023
Last Update
August 17 2022
Active Locations (5)
Enter a location and click search to find clinical trials sorted by distance.
1
Centre Médico-Social Jeanne Boutin
Bourail, Nouvelle Calédonie, New Caledonia
2
Centre hospitalier Territorial Gaston-Bourret
Noumea, Nouvelle Calédonie, New Caledonia
3
Centre hospitalier du Nord
Koné, New Caledonia
4
Centre hospitalier du Nord
Koumac, New Caledonia