Status:
WITHDRAWN
A Pilot Study of Repetitive Transcranial Magnetic Stimulation for Treatment of Methamphetamine Use Disorders
Lead Sponsor:
University of New Mexico
Collaborating Sponsors:
University of Iowa
University of Utah
Conditions:
Methamphetamine Abuse
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
We propose a single-arm clinical trial, with historical controls as a comparison group for select outcomes. Subjects with MAUD will receive 16 sessions of dual-target theta burst stimulation to the DL...
Detailed Description
Methamphetamine (MA) use can cause many serious adverse health consequences and is an important public health issue in Iowa, New Mexico, and Utah. In the 2017 Treatment Episode Data Set, 26% of substa...
Eligibility Criteria
Inclusion
- Diagnosed with an active methamphetamine use disorder
- Is engaged in psychosocial treatment or articulates a plan to engage in psychosocial treatment for methamphetamine use disorder during the study period
- Age 18 to 60 years
- Able to consent for treatment and research participation
- English-speaking
Exclusion
- Age less than 18 years (TMS not studied in pediatric population)
- Patients that are excluded during TMS assessment including: patients with epilepsy or seizure disorder, patients with implanted ferromagnetic equipment in their face or skull near the stimulation target.
- Current medical treatment with clozapine, bupropion, or stimulants.
- Current diagnosis of bipolar disorder, schizoaffective disorder, schizophrenia, or any other psychotic disorder.
- Legal or mental incompetency, or inability to consent to study.
- Unstable medical illness.
- Current diagnosis of neurological disorder or neurocognitive disorder.
- Prior neurosurgical procedure.
- History of seizure.
- History of ECT treatment within the past three months.
- History of any previous TMS treatment.
- Inability to complete the protocol, namely, inability to independently attend all study visits and TMS sessions on time.
- Prisoner
- Implanted device including pacemaker, coronary stent, defibrillator, or neurostimulation device that is not MRI-compatible
- Metal in body including bullets, shrapnel, metal slivers
- Claustrophobia
- Uncontrolled high blood pressure
- Atrial fibrillation
- Significant heart disease
- Hemodynamic instability
- Kidney disease
- Pregnant (MRI contraindicated during pregnancy)
- Unable to understand English (behavioral tests of impulsivity are only in English)
Key Trial Info
Start Date :
August 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 31 2021
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT04883021
Start Date
August 1 2020
End Date
May 31 2021
Last Update
September 30 2021
Active Locations (1)
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1
University of New Mexico Health Sciences Center
Albuquerque, New Mexico, United States, 87106