Status:
COMPLETED
Effect of Nitrous Oxide on EEG
Lead Sponsor:
Tampere University Hospital
Collaborating Sponsors:
Tampere University
University of Helsinki
Conditions:
Nitrous Oxide
Electroencephalography
Eligibility:
MALE
18-40 years
Phase:
PHASE1
Brief Summary
Our recent preclinical observations suggest that monitoring of slow electroencephalogram (EEG) oscillations may be used to predict the efficacy of rapid-acting antidepressants such as ketamine or nitr...
Eligibility Criteria
Inclusion
- informed consent obtained
- age between 18 - 40
- male
- body mass index 18 - 27
Exclusion
- Age \< 18 or \> 40
- Alcohol Use Disorders Identification Test (AUDIT) \>6 points
- Drug Abuse Screening Test 20 (DAST-20) \> 0 points
- Beck Depression Inventory (BDI) \> 11 points
- Symptom Check List 90 (SCL-90) over mean values of Finnish population in any dimensions of the SCL-90 or the global severity index
- Any respiratory disorder including sleep apnea
- Any heart illness
- Epilepsy
- Known vitamin B12 deficiency
Key Trial Info
Start Date :
May 21 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 24 2021
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04884893
Start Date
May 21 2021
End Date
September 24 2021
Last Update
December 10 2021
Active Locations (1)
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1
Tampere University Hospital
Tampere, Finland, 33521