Status:
COMPLETED
Diagnosis of Peripheral Lung Nodules Using Cryobiopsy
Lead Sponsor:
University of Zurich
Conditions:
Lung; Node
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
Since the traditional radial endobronchial ultrasound guided biopsy technique of solitary pulmonary nodules using the forceps has several shortcomings, the purpose of this study is to investigate a ne...
Detailed Description
This is a prospective randomized trial to assess diagnostic accuracy and safety of cryobiopsy using two different outer diameters. Included patients are 1:1 randomized to receive forceps biopsy follow...
Eligibility Criteria
Inclusion
- Solitary pulmonary nodule with indication of bronchoscopic diagnostic approach
- Age between 18 and 90 years
- Written informed consent after participant's information
Exclusion
- Age \< 18 and \> 90 years
- Lacking ability to form an informed consent (including impaired judgement, communi-cation barriers)
- Contraindication against bronchoscopy (e.g. co-morbidities)
- INR \> 2 or Thrombocytes \< 50000
- Double antiplatelet drugs (e.g. ASS and Clopidogrel) within 7 days before biopsy
- Anticoagulation with NOAK within 48 hours before biopsy
- Moderate or severe pulmonary hypertension (mPAP \> 30 mmHg, RV/RA \>30 mmHg)
- Tumors suspicious of endobronchial growth
Key Trial Info
Start Date :
April 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 30 2023
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT04885595
Start Date
April 1 2021
End Date
May 30 2023
Last Update
June 28 2024
Active Locations (1)
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1
University hospital Zurich
Zurich, Switzerland, 8091