Status:

ACTIVE_NOT_RECRUITING

Improving Diagnostic Accuracy for Acute Heart Failure

Lead Sponsor:

Vanderbilt University Medical Center

Collaborating Sponsors:

Wayne State University

Conditions:

Acute Heart Failure

Dyspnea

Eligibility:

All Genders

18+ years

Brief Summary

Acute heart failure is a common reason for emergency department visits and hospitalization, but the diagnosis can be challenging because of non-specific symptoms and signs. The current diagnostic appr...

Detailed Description

Acute heart failure (HF) is highly morbid, lethal, and costly. It is a difficult diagnosis to make given its symptoms and signs overlap with other cardiac and non-cardiac conditions. In the emergency ...

Eligibility Criteria

Inclusion

  • For enrollment into the prospective cohort for Outcome 3.
  • Willing to adhere to the study protocol
  • Able to provide written consent
  • English or Spanish speaking
  • Adult, defined as 18 years or older
  • Primary reason for presentation to the ED is dyspnea
  • ED physician is considering a diagnosis of HF, defined by ordering a NP test and/or a chest x-ray

Exclusion

  • History of end-stage renal disease for which hemodialysis is needed
  • Dyspnea due to primary presentation of an acute coronary syndrome or trauma

Key Trial Info

Start Date :

August 31 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 30 2026

Estimated Enrollment :

2800 Patients enrolled

Trial Details

Trial ID

NCT04886128

Start Date

August 31 2021

End Date

June 30 2026

Last Update

August 17 2025

Active Locations (1)

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Vanderbilt University Medical Center

Nashville, Tennessee, United States, 37232