Status:
UNKNOWN
Parameters Declaring PCO Infertile Patients Either Sensitive or Resistant to Different Doses of Clomiphene Citrate.
Lead Sponsor:
Ain Shams Maternity Hospital
Conditions:
PCO
Induction of Ovulation
Eligibility:
FEMALE
Up to 40 years
Brief Summary
Polycystic ovary syndrome (PCOS) is a common endocrinological disorder seen in 6%-10% of women (Human Reproduction, 2004). It is characterized by polycystic ovaries, anovulatory cycles, and hyperandro...
Detailed Description
All PCO patients under the age of 40 who are subfertile with no identified cause but PCO will undergo the following; * Detailed history taking including age, parity, medical, surgical history, previo...
Eligibility Criteria
Inclusion
- PCOS (based on Rotterdam's criteria: oligo/anovulation, hyperandrogenism clinical (hirsutism or less commonly male pattern alopecia) /biochemical (raised FAI or free testosterone) or polycystic ovaries on ultrasound(presence of 12 or more follicles in each ovary measuring 2-9 mm in diameter, and/or increased ovarian volume (\>10 ml)"1 . Unilaterality does not affect diagnosis; neither does the location of the cysts in the ovary.)
- Age \<40 years.
- Semen analysis within normal according to WHO 2010.
Exclusion
- Women on any insulin-sensitizing agent.
- Women on lipid-lowering agent.
- Women with endocrinal disorder (such as thyroid dysfunction, insulin resistance(DM), and adrenal disorders).
- Women diagnosed with anorexia nervosa/bulimia nervosa.
- Women with hypothalamic or pituitary dysfunction.
- Age \>40
- AMH level that does not reflect the phenotype of PCO
Key Trial Info
Start Date :
January 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2022
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04887402
Start Date
January 1 2021
End Date
March 1 2022
Last Update
February 16 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Ain Shams University
Cairo, Egypt