Status:

COMPLETED

Pediatric Language and Memory Mapping in Refractory Epilepsy Using Magnetoencephalography

Lead Sponsor:

University of Arkansas

Conditions:

Epilepsy

Eligibility:

All Genders

8-21 years

Brief Summary

This is a pilot research study where language and working memory tasks will be used to study brain activities from children with epilepsy. Specifically for language assessment, a well-known MEG langua...

Detailed Description

This is a pilot research study where language and working memory tasks will be used to study brain activities from children with epilepsy. Specifically for language assessment, a well-known MEG langua...

Eligibility Criteria

Inclusion

  • 8 to 21 years old
  • Drug-resistant focal epilepsy
  • Enrolled in the Arkansas Children's Neuroscience Center Comprehensive Epilepsy Program
  • Under evaluation for resective surgery
  • English speakers. This is not a treatment/intervention study.

Exclusion

  • Previous resective surgery for epilepsy
  • Presence of progressive neurodegenerative disorders
  • Presence of significant magnetic artifacts; electronic, magnetic or metallic implants (e.g. pins, screws, shrapnel remains, surgical clips, artificial heart valves, cochlear implants, vascular stents pacemakers); or permanent make-up or tattoos made with metallic dyes
  • Presence of seizures within 24 hours of the MEG
  • Use of sedation during the MEG acquisition
  • Inability to be in a seated or supine position during the tasks
  • Major medical disorders (e.g. HIV, cancer)
  • Significant visual or auditory disabilities
  • Physical disabilities that interfere with accomplishment of study tasks (when applicable)
  • Claustrophobia, or fear of cramped or confined spaces
  • Pregnancy or suspected pregnancy
  • Any condition that the investigator feels might put the patient at risk

Key Trial Info

Start Date :

July 14 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 22 2022

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT04888637

Start Date

July 14 2021

End Date

July 22 2022

Last Update

February 25 2025

Active Locations (1)

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University of Arkansas for Medical Sciences

Little Rock, Arkansas, United States, 72205