Status:

COMPLETED

Optimizing Timing of Follow-up Colonoscopy

Lead Sponsor:

University of Manitoba

Conditions:

Colo-rectal Cancer

Colon Polyp

Eligibility:

All Genders

50-75 years

Phase:

NA

Brief Summary

Overall Objective: To optimize timing of surveillance colonoscopy. Principal research question and specific aims: To assess the impact of access to a hand-held application on the timing of surveillan...

Detailed Description

Study design and intervention: This will be a cluster randomized controlled trial in which individual endoscopy physicians (gastroenterologists and surgeons) will be randomized (stratified by physicia...

Eligibility Criteria

Inclusion

  • For physician participants, there are no age limits/parameters. All physicians performing colonoscopy on adult patients in Winnipeg will be eligible to participate (other than those involved in pilot testing and study investigators). Participating physicians will be informed that the introduced intervention will be an information tool to help improve care for individuals undergoing colonoscopy, and will be asked to consent to review of their patient records. Participating physicians will be informed that no individual-level information will be disclosed at any time and all analysis will be on anonymized data.
  • For patient participants:
  • Patients must be older than 50 years and up to 75 years old for inclusion in the study data.
  • Adequate bowel preparation defined by Boston Bowel Preparation Scale Score of ≥ 2 in each of segments of the colon (Boston bowel prep scale score recording is mandatory in the Winnipeg city-wide endoscopy reporting system);
  • Colonoscopy completed to the cecum/ileocolonic anastomosis;
  • Colonoscopy performed between 1 to 4 months before randomization of endoscopy physician (to determine baseline adherence) or between 3 to 7 months after randomization (to determine effect of the intervention).

Exclusion

  • Physicians will be excluded if they are away for more than six weeks continuously in the six months after randomization. In this situation, an alternate physician will be recruited and randomized. Thus there is no anticipated loss of follow-up.
  • Patients will be excluded if any of the following criteria are met:
  • History of inherited CRC predisposition (Lynch Syndrome, Familial adenomatous polyposis, others);
  • Inflammatory bowel disease;
  • Partially excised polyp or endoscopy physician recommending early colonoscopy to document complete excision;
  • Endoscopy physician documenting a rationale for not repeating colonoscopy in future such as co-morbid conditions.

Key Trial Info

Start Date :

July 15 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2022

Estimated Enrollment :

29 Patients enrolled

Trial Details

Trial ID

NCT04889352

Start Date

July 15 2021

End Date

December 31 2022

Last Update

April 6 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Health Sciences Center

Winnipeg, Manitoba, Canada, R3E 3P4

2

Winnipeg Regional Health Authority

Winnipeg, Manitoba, Canada, R3E 3P4