Status:
COMPLETED
Spontaneous Healing of ARticular Cartilage (SHARC)
Lead Sponsor:
Keele University
Collaborating Sponsors:
Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Conditions:
Cartilage Damage
Cartilage Injury
Eligibility:
All Genders
18+ years
Brief Summary
SHARC is an observational study of cartilage patients who are treated with surgery that involves obtaining a harvest biopsy. SHARC will study the natural healing process of the harvest biopsy site bas...
Detailed Description
Osteoarthritis (OA) is a very common disease of the joints, for which in the United Kingdom alone almost 9 million people have sought treatment. This painful disease affects the cartilage and bone ins...
Eligibility Criteria
Inclusion
- Being able to provide signed and dated informed consent form.
- Scheduled for one of the following surgical treatments
- Surgery that involves the harvest of cartilage tissue as part of the treatment, thus creating a fresh cartilage defect, which is then left to heal naturally. Examples of such surgery are autologous chondrocyte implantation (ACI) and mosaicplasty.
- Autologous stromal cell implantation (ASCI), as part of the ASCOT randomised clinical trial.
Exclusion
- Inadequate understanding of verbal explanations or written information given in English, or having special communication needs.
- Chronic severe renal insufficiency
- Anything that would preclude the individual's full compliance with or completion of the study.
Key Trial Info
Start Date :
September 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2023
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT04889443
Start Date
September 1 2018
End Date
December 31 2023
Last Update
March 13 2024
Active Locations (1)
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1
RJAH Orthopaedic Hospital NHS Foundation Trust
Oswestry, Shropshire, United Kingdom, SY10 7AG