Status:

COMPLETED

Blood Flow Restricted Resistance Training in Peripheral Arterial Disease

Lead Sponsor:

Sheffield Hallam University

Collaborating Sponsors:

Sheffield Teaching Hospitals NHS Foundation Trust

Conditions:

Peripheral Arterial Disease

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

A randomised controlled trial evaluating the feasibility and acceptability of a 12 week lower body blood flow restricted resistance exercise programme for people with peripheral arterial disease.

Detailed Description

The primary aim of this study is to determine the feasibility of 12 weeks of lower body resistance exercise performed with blood flow restriction (BFR) in people with peripheral arterial disease. Res...

Eligibility Criteria

Inclusion

  • Men and women with PAD 6 months post diagnosis.
  • Ankle-brachial pressure index \<0.9.
  • People physically able to perform leg press and leg extension resistance exercise.

Exclusion

  • Ankle-brachial pressure index \>0.89.
  • People unable to visit the laboratory twice weekly for exercise sessions.
  • People unable to do leg press and leg extension exercise.
  • People whose walking is limited by a non-PAD condition.
  • People with PAD with critical limb ischemia (including symptoms of pain at rest and skin ulcers).
  • People with Dementia.
  • People who have had major surgery or myocardial infarction within the past 6 months.
  • Previous stroke.
  • Previous thrombosis.
  • People who have major surgery scheduled during the intervention period.

Key Trial Info

Start Date :

April 21 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 30 2022

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04890275

Start Date

April 21 2021

End Date

April 30 2022

Last Update

November 8 2022

Active Locations (1)

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Sheffield Hallam University

Sheffield, South Yorkshire, United Kingdom, s10 2BP