Status:
UNKNOWN
Stereotactic Pelvic Adjuvant Radiation Therapy in Cancers of the Uterus II
Lead Sponsor:
Sunnybrook Health Sciences Centre
Collaborating Sponsors:
Princess Margaret Hospital, Canada
Royal Victoria Hospital, Canada
Conditions:
Endometrial Cancer
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
Adjuvant radiotherapy (RT) plays an important role in reducing the risks of local recurrence after surgery in uterine cancers. Standard adjuvant pelvic radiation treatment targets the pelvic lymph nod...
Eligibility Criteria
Inclusion
- Patient with histologically confirmed endometrial adenocarcinoma, serous or clear cell carcinoma.
- Patient is a candidate for adjuvant pelvic radiation for uterine cancer (+/- vault brachytherapy), meeting one of the following conditions:
- High grade histology (including serous and clear cell) OR Outer-half myometrial invasion and International Federation of Gynecology and Obstetrics (FIGO) grade 1-2 OR FIGO stage II - III.
- Patients who are to receive adjuvant systemic therapy sequentially in addition to pelvic radiotherapy will be eligible.
- Age ≥18 years.
- Patient is willing and able to give informed consent to participate in this clinical trial.
Exclusion
- Patient has had prior pelvic radiotherapy.
- Patient has a contraindication to pelvic radiotherapy, such as but not limited to a connective tissue disease or inflammatory bowel disease.
- Patient planned for concurrent chemoradiation therapy.
Key Trial Info
Start Date :
July 15 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2023
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04890912
Start Date
July 15 2021
End Date
June 1 2023
Last Update
October 25 2021
Active Locations (5)
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1
Royal Victoria Hospital
Barrie, Ontario, Canada, L4M 6M2
2
London Regional Cancer Program
London, Ontario, Canada, N6A 5W9
3
Credit Valley Hospital
Mississauga, Ontario, Canada, L5M 2N1
4
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada, M4N 3M5