Status:

COMPLETED

Embr Thermal Device for Hot Flash Management in Prostate Cancer

Lead Sponsor:

Embr Labs, Inc.

Conditions:

Prostate Cancer

Hot Flashes

Eligibility:

MALE

18+ years

Phase:

NA

Brief Summary

This study is being conducted to evaluate if the Embr thermal device is useful for men who experience bothersome hot flashes as a result of prostate cancer treatment.

Detailed Description

The Embr thermal device is a smart device that is worn on the inside of the wrist. It is about the size of a smart watch. The Embr thermal device produces cooling or warming temperature sensations tha...

Eligibility Criteria

Inclusion

  • Have received a diagnosis of prostate cancer and have received treatment with GnRH agonist or antagonist therapy or orchiectomy at least 1 month prior to enrollment.
  • May have received prior definitive radiation therapy or surgery (\>60 days prior to study).
  • Have bothersome hot flashes (occurrence ≥ 28 times per week and at least moderately bothersome).
  • Presence of hot flashes for \>30 days prior to study entry.
  • Have a working smartphone (iPhone 6 or greater; or Android 8.0 or greater).
  • Willing to downloading and use the Embr thermal device companion app on their phone
  • Willing to wear the Embr thermal device for 4 weeks, and charge and sync the device daily
  • In order to complete the mandatory patient-completed measures, participants must be able to speak and/or read English

Exclusion

  • Planned treatment with chemotherapy and/or any medical intervention that will impact hot flashes, sleep, or other daily activities of daily life during the 4-week study.
  • History of a known sleep disorder, other than insomnia (eg, obstructive sleep apnea, restless leg syndrome), or medical or psychiatric condition that affects sleep, or undergoing treatment for insomnia.
  • History of cognitive impairment or dysfunction.
  • Seizure history, history of recurrent falls, or known brain metastases.
  • Uncontrolled intercurrent illness.
  • Individuals with a second malignancy other than non-melanoma skin cancers.
  • Individuals taking psychotropic medications or illicit drugs that may alter cognition, concentration, or behavior.
  • Individuals taking prescription sleep medications.
  • Individuals who report consuming more than 7 alcoholic beverages/week and/or frequent alcohol consumption within 2 hours prior to bed.

Key Trial Info

Start Date :

May 28 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 5 2021

Estimated Enrollment :

57 Patients enrolled

Trial Details

Trial ID

NCT04892914

Start Date

May 28 2021

End Date

December 5 2021

Last Update

April 5 2022

Active Locations (1)

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Embr Labs (Remote study site)

Boston, Massachusetts, United States, 02129