Status:
TERMINATED
Inflammatory Consequences of Crystalloids in Severely Burned Patients
Lead Sponsor:
Centre hospitalier de l'Université de Montréal (CHUM)
Conditions:
Burns
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This is a pilot study, but the investigators will also observe key immunological events with potential significance. The global objective is to study the inflammatory profiles of PlasmaLyte and Ringer...
Detailed Description
The investigators have 4 specific objectives. First, the investigators will compare the activation profiles of macrophages and neutrophils in patients admitted to the severely burned unit with regards...
Eligibility Criteria
Inclusion
- admission to the CHUM
- more than 20% of burned area
- first blood withdrawal in the first 24 hours following burn
Exclusion
- immunosuppression
- chemotherapy 6 months before admission
- radiotherapy 6 months before admission
- autoimmune diseases
- neoplasia
- pregnancy
- severe infections
- cardiac dysfunctions
- renal dysfunction
- hepatic dysfunctions
- Hepatitis C
- HIV
Key Trial Info
Start Date :
October 17 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 19 2025
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT04893382
Start Date
October 17 2021
End Date
February 19 2025
Last Update
February 21 2025
Active Locations (1)
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1
CHUM
Montreal, Quebec, Canada, h2X0C1