Status:

UNKNOWN

Impact of V106I on Resistance to Doravirine

Lead Sponsor:

Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental

Conditions:

HIV-1-infection

Eligibility:

All Genders

13-75 years

Brief Summary

Objective. To study the impact of V106I mutation in the reverse transcriptase of HIV-1 on the activity of Doravirine. Clinical hypotheses. Doravirine shows a unique resistance pattern with a higher ...

Detailed Description

Testing for transmitted drug resistance (TDR) in the reverse transcriptase and protease in newly diagnosed patients with HIV is recommended by treatment guidelines. Currently clinical practice for fir...

Eligibility Criteria

Inclusion

  • Antiretroviral-naïve subjects over 13 years of age, including both seroprevalent and seroconverter patients

Exclusion

  • Patients with prior antiretroviral exposure
  • \-

Key Trial Info

Start Date :

September 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 1 2022

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT04894357

Start Date

September 1 2021

End Date

May 1 2022

Last Update

August 18 2021

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Impact of V106I on Resistance to Doravirine | DecenTrialz