Status:
COMPLETED
Brain Responses to Contextual Influences on Drinking Decisions
Lead Sponsor:
University of Kansas Medical Center
Collaborating Sponsors:
University of Kansas
Conditions:
Alcohol Drinking
Eligibility:
All Genders
21-55 years
Phase:
NA
Brief Summary
This study is using functional magnetic resonance imaging (fMRI) to examine brain activity associated with making decisions about drinking alcohol in everyday situations, some of which may involve imp...
Detailed Description
The overall objective of this study is to examine brain activity associated with making decisions about drinking alcohol in everyday situations, some of which may involve important activities happenin...
Eligibility Criteria
Inclusion
- 21-55 years of age;
- current heavy alcohol drinking in the past three months, as indicated by reporting consumption of 14 or more drinks per week for men or 7 or more drinks per week for women and at least one heavy drinking episode weekly (5+/4+ drinks in a single occasion for males/females);
- belong to a category with significant responsibilities, such as being currently employed, a current student, or a caregiver with significant responsibilities;
- speak English;
- normal or corrected to normal vision and hearing;
- able to give informed consent.
Exclusion
- currently engaged in treatment or seeking treatment for alcohol-related problems;
- major psychiatric illness (psychotic disorder, bipolar disorder, post-traumatic stress disorder);
- Diagnostic and Statistical Manual Version-5 substance use disorder (except nicotine);
- attending any in-person session with a positive breath alcohol concentration (BrAC \> 0.00%);
- any contraindications for MRI scanning (e.g., metal in body surgically or accidentally including pacemaker, cochlear implants, aneurysm clips, shrapnel, etc.);
- history of seizures or anti-seizure medication;
- history of concussion or other significant brain injury;
- serious medical illness unsuitable for the MRI scanner based on best clinical judgment
Key Trial Info
Start Date :
February 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 31 2025
Estimated Enrollment :
52 Patients enrolled
Trial Details
Trial ID
NCT04895033
Start Date
February 1 2023
End Date
July 31 2025
Last Update
November 14 2025
Active Locations (1)
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1
Cofrin Logan Center for Addiction Research and Treatment
Lawrence, Kansas, United States, 66045