Status:

UNKNOWN

Treatment With Pyrotinib-Based Therapy in Lapatinib Resistant HER2-Positive Metastatic Breast Cancer

Lead Sponsor:

The First Affiliated Hospital with Nanjing Medical University

Conditions:

Breast Cancer

Eligibility:

FEMALE

18-70 years

Brief Summary

This is a multicenter, observational, single-arm real world study to evaluate the efficacy and safety of pyrotinib after lapatinib progression.

Detailed Description

HER2-positive breast cancers account for 15%-20% of all breast cancers. The development of HER2 targeted therapies have greatly improved the survival of HER2-positive breast cancer patients. Lapatinib...

Eligibility Criteria

Inclusion

  • Female and 18-70 years old
  • Metastatic or locally recurrent HER2-positive breast cancer
  • Patients received pyrotinib-based therapy after lapatinib failure in treatment for metastasis
  • Complete and accurate medical data

Exclusion

  • \- Incomplete medical data

Key Trial Info

Start Date :

August 1 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2021

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04899128

Start Date

August 1 2018

End Date

June 1 2021

Last Update

May 24 2021

Active Locations (1)

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Jiangsu Provincial People's Hospital

Nanjing, Jiangsu, China