Status:

COMPLETED

Tahiti-families: Polynesian Families of Gout Patients

Lead Sponsor:

Lille Catholic University

Collaborating Sponsors:

Variant Bio, Inc.

University of Birmingham

Conditions:

Gout

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

Gout is a chronic disease caused by the deposit of monosodium urate (MSU) crystals in body tissues secondary to hyperuricemia. Patients with gout suffer severe attacks of acute joint pain. As the dise...

Eligibility Criteria

Inclusion

  • Inclusion Criteria :
  • Case group :
  • Gout patients
  • Polynesian origin
  • Aged 18 to 80 years
  • Agreeing to participate in the study
  • Having a 1st or 2nd degree relative who is also gouty and a 1st degree relative of the same generation and sex who is not gouty
  • Control group :
  • Non-gouty individuals who are 1st degree relatives of a gouty patient of the same generation and sex
  • Aged 18 to 80 years
  • Agreeing to participate in the study
  • Exclusion Criteria :
  • Pregnant women
  • Persons under guardianship, curatorship or other legal incapacity
  • Persons with a contraindication to Magnetic resonance imaging (MRI) examination
  • For non-gouty controls : current hyperuricemic treatment (Allopurinol, Febuxostat, Probenecid or Benzbromarone)
  • For gouty case : not participating in the TOPATA study (NCT04812886)

Exclusion

    Key Trial Info

    Start Date :

    May 25 2021

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    August 31 2021

    Estimated Enrollment :

    33 Patients enrolled

    Trial Details

    Trial ID

    NCT04900090

    Start Date

    May 25 2021

    End Date

    August 31 2021

    Last Update

    March 6 2024

    Active Locations (1)

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    Centre Hospitalier de Polynésie Française

    Papeete, Ville de Pirae, French Polynesia, 98713