Status:
COMPLETED
Evaluation of SARS-COV-2 Viral Load of Covid-19 Patients After Rinsing With Oral Antimicrobial Mouthwashes
Lead Sponsor:
Hospital Israelita Albert Einstein
Collaborating Sponsors:
Colgate Palmolive
Conditions:
Covid19
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
The aim of this study is to analyze the efficacy of oral disinfection with 0.075% Cetylpyridinium Chloride alone and 0.075% Cetylpyridinium Chloride associated with 0.28% zinc lactate in reduction of ...
Detailed Description
Each group of patients will receive specific interventions, as follows: 0.075% Cetylpyridinium Chloride mouthwash (Group 1); 0.075% Cetylpyridinium Chloride associated with 0.28% zinc lactate mouthwas...
Eligibility Criteria
Inclusion
- positive for SARS-CoV-2 by the RT-PCR method,
- in common bed for minimum of 1 day and maximum of 5 days,
- ensuring that patients are no more than 10 days since showing the first symptoms,
- who are positive for SARS-CoV-2 in the first collection of oral fluid and saliva, and
- who demands oral hygiene care and other preventive and therapeutic dental procedures.
Exclusion
- pediatric patients, t
- hose who tested negative for SARS-CoV-2 by the RT-PCR method at the time of recruitment or at the time of first oral fluid and saliva collection;
- those who exhibit oral ulcerations and other erosive lesions in the oral mucosa, which contraindicate the use of cetylpyridinium;
- patients who have bleeding in the oral cavity which prevents sample collections; patients who report history of allergy, irritations or other side effects derived from the use of these substances;
- patients who do not adhere to oral care protocols or those in whom it was not possible to perform these procedures.
Key Trial Info
Start Date :
April 4 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 30 2021
Estimated Enrollment :
105 Patients enrolled
Trial Details
Trial ID
NCT04902976
Start Date
April 4 2021
End Date
October 30 2021
Last Update
March 11 2022
Active Locations (1)
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1
Hospital israelita Albert Einstein
São Paulo, Brazil, 05652-900