Status:
ENROLLING_BY_INVITATION
External Nitric Oxide Measurement Through SNO Degradation
Lead Sponsor:
Indiana University
Conditions:
Healthy
Unconscious
Eligibility:
All Genders
1-75 years
Phase:
NA
Brief Summary
In this study, we aim to explore the feasibility of a novel, noninvasive SNO assay to acquire physiological SNO quantification from various parts of the human body and test this new method of analysis...
Detailed Description
S-nitrosylation is the covalent attachment of a nitric oxide group to cystine thiol within a protein to form an S-nitrosothiol (SNO); it has diverse regulatory roles in all mammalian cells and thus op...
Eligibility Criteria
Inclusion
- Inclusion Criteria
- Adult males or females age ≥ 1 day and ≤ 75 years at time of enrollment
- Exclusion Criteria
- Subjects meeting the following criteria will be excluded:
- Smokers.
- Any chronic skin conditions.
- Pregnant.
- Subjects that are unable or unwilling to cooperate with specimen collection.
- Subjects with diagnosis of any medical condition that in the investigator's opinion would make them unsuitable for study participation.
- (for subjects ≥ 18) Subjects that lack the capacity to consent for themselves.
Exclusion
Key Trial Info
Start Date :
May 10 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2025
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT04903535
Start Date
May 10 2021
End Date
December 30 2025
Last Update
December 10 2024
Active Locations (2)
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1
Riley Hospital for Children
Indianapolis, Indiana, United States, 46202
2
Wells Center for Pediatric Research
Indianapolis, Indiana, United States, 46202