Status:
RECRUITING
Nebulized Tranexamic Acid in Sinus Surgery
Lead Sponsor:
Assiut University
Conditions:
Bleeding Nose
Eligibility:
All Genders
18-65 years
Phase:
PHASE3
Brief Summary
The results of several recent studies on endoscopic sinus surgery through topical administration of tranexamic acid are encouraging in terms of the efficacy of tranexamic acid for intraoperative bleed...
Detailed Description
A written informed consent will be taken from the patients.The study involved adults of either sexes (age 18-65 years) of ASA I-II who will be listed for elective functional endoscopic sinus surgery (...
Eligibility Criteria
Inclusion
- Either sexes (age 18-65 years) of ASA I-II who are listed for elective functional endoscopic sinus surgery (FESS) under general anesthesia
- normal accepted coagulation profile and hematocrit value ≥30
Exclusion
- chronic renal failure
- liver cirrhosis
- bleeding disorders
- current anticoagulant therapy
- pregnancy or breastfeeding
- impaired color vision
- severe vascular ischemia
- history of venous thrombosis, pulmonary embolism
- long term treatment with acetylsalicylic acid or non-steroidal anti-inflammatory drugs not discontinued before surgery
- hemoglobin (HB) concentration \<10 mg/dl \_allergy to TXA.
Key Trial Info
Start Date :
May 6 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 25 2025
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT04905901
Start Date
May 6 2021
End Date
December 25 2025
Last Update
August 5 2025
Active Locations (1)
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1
Assuit
Asyut, Assuit, Egypt, Assuit universi