Status:
COMPLETED
The Therapeutic Effects of Forced Aerobic Exercise in Multiple Sclerosis
Lead Sponsor:
The Cleveland Clinic
Conditions:
Multiple Sclerosis
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
This project will investigate the feasibility and initial efficacy of two aerobic exercise training approaches, forced and voluntary, to improve motor function in persons with multiple sclerosis (MS)....
Detailed Description
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervous system characterized by progressive loss of motor function, cognitive function, in addition to sy...
Eligibility Criteria
Inclusion
- Confirmed diagnosis of RRMS with Expanded Disability Status Scale (EDSS) score between 1.5 and 6.5,
- 18-75 years of age,
- Deemed minimal risk for cardiovascular event using American College of Sports Medicine Exercise Pre-participation Criteria
Exclusion
- hospitalization for myocardial infarction, heart failure or heart surgery within 3 months,
- serious cardiac arrhythmia,
- hypertrophic cardiomyopathy,
- severe aortic stenosis,
- pulmonary embolus,
- significant contractures,
- dysphagia resulting in inability to sufficiently hydrate, and
- other contraindication to exercise.
Key Trial Info
Start Date :
July 6 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 29 2022
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT04906057
Start Date
July 6 2021
End Date
November 29 2022
Last Update
March 6 2025
Active Locations (2)
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1
Cleveland Clinic Main Campus
Cleveland, Ohio, United States, 44195
2
Cleveland Clinic
Cleveland, Ohio, United States, 44195