Status:
COMPLETED
Dexmedetomidine-ketamine Versus Propofol-ketamine for Sedation During Endoscopy in Hepatic Patients
Lead Sponsor:
Tamer Nabil Abdelrahman
Conditions:
Anesthesia; Reaction
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
We aim to compare the response to ketamine/dexmedetomidine and ketamine/propofol combinations used in hepatic patients with child-Pugh classification (class A), and early (class B) undergoing UGIE.
Detailed Description
70 Patients will be randomly allocated into two groups; Group (KD): Ketamine/dexmedetomidine (35 patients), will receive IV ketamine 0.25mg/kg and dexmedetomidine1µg/kg over 10 min as loading followed...
Eligibility Criteria
Inclusion
- hepatic patients with child-Pugh classification (class A), and (class B)
- American Society of Anesthesiologists physical status II, III
- aged 18 to 60 years
- scheduled for elective Upper gastro-intestinal endoscopy.
Exclusion
- emergency gastro-intestinal endoscopy.
- patients with severe hepatic disorder (Child C) ,
- chronic neuro-psychiatric disorder,
- history of neuro-psychiatric drug intake,
- severe cardiovascular diseases,
- pregnancy,
- history of drug abuse, and
- history of allergy to any of the used drugs in the study
Key Trial Info
Start Date :
February 3 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2021
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT04906772
Start Date
February 3 2021
End Date
September 30 2021
Last Update
January 31 2024
Active Locations (1)
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1
Faculty of medicine, Ain-Shams university
Cairo, Egypt