Status:

UNKNOWN

Methadone Anesthesia For Kidney Transplant Receptors

Lead Sponsor:

University of Sao Paulo General Hospital

Conditions:

Renal Failure Chronic

Surgery

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

Intraoperative methadone or fentanyl will be administered to patients submitted to kidney transplant surgery. Postoperative pain, analgesic consumption and side effects will be evaluated

Detailed Description

Despite recent developments in postoperative pain control, many patients still experience moderate or severe pain after surgery. It is estimated that severe postoperative pain occurs in 20 to 40% of s...

Eligibility Criteria

Inclusion

  • Patients over 18 years of age
  • With indication for kidney transplant surgery
  • Who sign the informed consent form

Exclusion

  • Patients who refuse to participate in the study
  • Known allergy to any drug used in this protocol
  • Presence of stage III or IV congestive heart failure
  • Increase in QT interval on electrocardiogram (QT\> 500 msec)
  • Preemptive kidney transplantation (defined by transplantation in a patient who has not yet started kidney replacement therapy).

Key Trial Info

Start Date :

May 17 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2022

Estimated Enrollment :

32 Patients enrolled

Trial Details

Trial ID

NCT04908345

Start Date

May 17 2021

End Date

January 1 2022

Last Update

June 1 2021

Active Locations (1)

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1

Hospital das Clínicas da FMUSP

São Paulo, São Paulo, Brazil, 05403-000