Status:
UNKNOWN
Reducing Air Pollution to Lower Blood Pressure
Lead Sponsor:
Wayne State University
Conditions:
Mild Hypertension
Air Pollution Exposure
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Fine particulate matter \<2.5 μm (PM2.5) air pollution is the fifth leading risk factor for global mortality. Mitigating the clinically significant blood pressure (BP) elevation from air pollution by ...
Detailed Description
1. Air pollution caused by fine particulate matter with aerodynamic diameter \<2.5 μm (PM2.5) is the fifth leading risk factor for global mortality,1,2 predominantly due to cardiovascular disease (CVD...
Eligibility Criteria
Inclusion
- Self-reported nonsmokers (for at least last year)
- Has own smartphone
- Systolic BP (SBP) at 120-145 mmHg
- Diastolic blood pressure (DBP) \<95 mmHg
- Has history of hypertension with ≤ 3 medications and stable without change in past 3 months
- If medications are used, there should be no change in dosage during the 28-day study period.
Exclusion
- Living with an active smoker who smokes indoors
- Left upper arm circumference \>17 inches (measured by tape measure upon recruitment as needed as it makes the home BP device inaccurate)
- Pregnant
- Unable/unwilling to consent
- Established cardiovascular disease (CVD)
- Stage IV clinical kidney disease (CKD)
- Clear barrier to technology use (e.g., visual or hearing impairment)
- Lung disease requiring oxygen
- Cancer receiving treatment
- Diabetes
- COVID-19 infections
- Any condition where the investigators believe the risk of a mildly high BP above 130/80 mmHg may pose risk to the patient during the 28-day period of the study including but not limited to aortic aneurysms
Key Trial Info
Start Date :
July 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2023
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04908917
Start Date
July 1 2021
End Date
July 1 2023
Last Update
June 1 2021
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