Status:

UNKNOWN

CDDOM Oneome Rightmed Depression Study

Lead Sponsor:

University of Arizona

Collaborating Sponsors:

OneOme, LLC

Conditions:

Depression, Anxiety

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

In this study, we hypothesize PGx guided testing can improve outcomes related to treatment of moderate and severe depression among El Rio Community Health patients. We anticipate patients randomized t...

Detailed Description

In this study, we hypothesize PGx guided testing can improve outcomes related to treatment of moderate and severe depression among El Rio Community Health patients. We anticipate patients randomized t...

Eligibility Criteria

Inclusion

  • 18-80 years of age
  • PHQ-9 score ≥ 10
  • Suffer from Major Depressive Disorder meeting DSM-V criteria and meet at least one of the following:
  • Either new to antidepressant treatment or currently taking medication for less than 6 weeks.
  • Inadequate efficacy after at least 6 weeks of antidepressant treatment
  • Have discontinued antidepressant treatment due to adverse events or intolerability within the last 6 weeks
  • Must be able to understand requirements of the study and provide written informed consent (English or Spanish)

Exclusion

  • Any patient for whom providing a buccal swab sample would be contraindicated or not possible.
  • Patients taking antidepressants for \> 6 months consecutively prior to baseline unless determined to be inadequate efficacy and PCP looking to change medication.
  • Subjects diagnosed as not having or depression.
  • Patients with history of prior PGx testing
  • Inability to provide informed consent
  • Current diagnosis of bipolar disorder type I or II, psychosis, schizophrenia and/or schizoaffective disorder
  • Inability to attend scheduled study visits
  • Patients who are known to be pregnant or lactating
  • Patients that are diagnosed with severe depression

Key Trial Info

Start Date :

June 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2023

Estimated Enrollment :

350 Patients enrolled

Trial Details

Trial ID

NCT04909749

Start Date

June 1 2021

End Date

June 1 2023

Last Update

June 2 2021

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